Dr. Jian YIN
Jiangnan University
E-mail: jianyin@jiangnan.edu.cn
Professional position
2023/03 – Dean, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, P. R. China
2019/05 – Board Member, University Academic Committee &
Board Chair, University Appointments and Promotions Subcommittee affiliated with University Academic Committee, Jiangnan University, Wuxi, P. R. China
2013/10 – Head, Max-Planck Society International Partner Group in China (with MPIKG Potsdam)
2012/01 – Principal Investigator/Professor, School of Biotechnology, Jiangnan University, Wuxi, P. R. China
Scientific background
2009/04–2011/12 Postdoc associate, Department of Biomolecular Systems, Max-Planck Institute of Colloids & Interfaces, Berlin, Germany (with Prof. Peter H. Seeberger)
2005/11–2009/03 Ph.D., Department of Chemistry, University of Potsdam, Potsdam, Germany (with Prof. Torsten Linker)
2002/09–2005/07 M. Sc., School of Pharmacy, China Pharmaceutical University, Nanjing, P. R. China (with Prof. Yihua Zhang)
1997/09–2001/07 B. Sc., School of Chemistry and Materials Science, Nanjing Normal University, Nanjing, P. R. China
Awards and honors
2023 National Science Fund for Distinguished Young Scholars, China
2023 NHU-CJC Innovation Award, China
2021 Thieme Chemistry Journals Award,Germany
2021 Tomoya Ogawa Young Investigator Award, the USA
2021 Zhang Tianmin Carbohydrate-based Drug Award for Outstanding Youth Glycoscientist, China
2021 Jiangsu Teaching Achievement Award, Jiangsu Province
2019 Zhang Shuzheng Glycoscience Award for Outstanding Young Glycoscientist, China
2019 National Virtual Simulation Teaching Project, MOE, China
2018 National Teaching Achievement Award, MOE, China
2018 Jiangsu Science Fund for Distinguished Young Scholars, Jiangsu Province
2017 Jiangsu Teaching Achievement Award, Jiangsu Province
2017 Outstanding Mentor for National Innovation and Entrepreneurship Training Program, MOE, China
2016 Nomination Award for the Man of the Year in Education, Wuxi City
2015 Innovation and Entrepreneurship Talent, Jiangsu Province
2013 Max-Planck Society International Partner Group Fellowship, Germany
2012 National Distinguished Young Professorship, China
Editorial work
2024- Editorial Board Member, Chinese Journal of Natural Medicines
2024- Editorial Board Member, Chinese Journal of Modern Applied Pharmacy (in Chinese)
2024- Editorial Board Member, Progress in Pharmaceutical Sciences (in Chinese)
2019- Editorial Board Member, Carbohydrate Research
2019- Editorial Board Member, Journal of Carbohydrate Chemistry
Board Memberships
2022- Vice-Chairman and Secretary General, Carbohydrate-based Vaccines Committee, China Association for Vaccines
2022- the Board Member, Pharmaceutical and Chemical Engineering Division, Chemical Industry and Engineering Society of China
2021- the Board Member, Glycobiology Division, Biophysical Society of China
2020- the Board Member, Carbohydrate Drugs Division, China Biochemical Pharmaceutical Industry Association
2019- the Board Member, Carbohydrate Chemistry Division, Chinese Chemical Society
2017- the Board Member, Glycobiotechnology Division, Chinese Society of Biotechnology
Research interests
Carbohydrate-based vaccine and drug development
Representative publications
1. “Chemical synthesis of the highly sterically hindered core undecasaccharide ofHelicobacter pylorilipopolysaccharide for antigenicity evaluation with human serum”, Xiaopeng Zou, Jing Hu, Ming Zhao, Chunjun Qin, Yuntao Zhu, Guangzong Tian, Juntao Cai, Peter H. Seeberger, Jian Yin*.J. Am. Chem. Soc.,2022,144, 14535-14547.
2. “Chemical synthesis and antigenicity evaluation ofShigella dysenteriaeserotype 10 O‑antigen tetrasaccharide containing a (S)‑4,6‑O‑pyruvyl ketal”, Chunjun Qin, Lingxin Li, Guangzong Tian, Meiru Ding, Shengyong Zhu, Wuqiong Song, Jing Hu, Peter H. Seeberger, Jian Yin*.J. Am. Chem. Soc.,2022,144, 21068-21079.
3. “Total synthesis of a densely functionalizedPlesiomonas shigelloidesserotype 51 aminoglycoside trisaccharide antigen”, Chunjun Qin, Benjamin Schumann, Xiaopeng Zou, Claney L. Pereira, Guangzong Tian, Jing Hu, Peter H. Seeberger*, Jian Yin*.J. Am. Chem. Soc.,2018,140, 3120-3127.
4. “Chemical synthesis elucidates the key antigenic epitope of the autism‐related bacteriumClostridium bolteaecapsular octadecasaccharide”, Juntao Cai, Jing Hu, Chunjun Qin, Lingxin Li, Dacheng Shen, Guangzong Tian, Xiaopeng Zou, Peter H. Seeberger, Jian Yin*.Angew. Chem. Int. Ed.,2020,59, 20529-20537.
5. “Chemical synthesis and immunological evaluation ofHelicobacter pyloriserotype O6 tridecasaccharide O-antigen containing a DD-heptoglycan”, Guangzong Tian, Jing Hu, Chunjun Qin, Lingxin Li, Xiaopeng Zou, Juntao Cai, Peter H. Seeberger, Jian Yin*.Angew. Chem. Int. Ed.,2020,59, 13362-13370.
6. “Chemical synthesis and antigenic evaluation of inner core oligosaccharides fromAcinetobacter baumanniilipopolysaccharide”, Xianyang Zhou, Lingxin Li, Zhen Zhang, Shichao Duan, Yingwen Huang, Yiyang Luo, Xiadong Mu, Zhiwei Chen, Yong Qin, Jing Hu, Jian Yin*, Jinsong Yang*.Angew. Chem. Int. Ed.,2022,61, e202204420.
7. “Fabrication of glyco-metal-organic frameworks for targeted interventional photodynamic/chemotherapy for hepatocellular carcinoma through percutaneous transperitoneal puncture”, Jun Hu,Wenrui Wu, Yufei Qin, Chao Liu, Peng Wei, Jing Hu, Peter H. Seeberger, Jian Yin*.Adv. Funct. Mater.,2020,30, 1910084.
8. “An integrated therapeutic delivery system for enhanced treatment of hepatocellular carcinoma”, Zhou Ye, Wen-rui Wu, Yu-fei Qin, Jing Hu, Chao Liu*, Peter H. Seeberger*, Jian Yin*.Adv. Funct. Mater.,2018,28, 1706600.
9. “Evoking and enhancing ferroptosis of cancer stem cells by a liver-targeted and metal-organic framework-based drug delivery system inhibits the growth and lung metastasis of hepatocellular carcinoma”, Pengfei Zhang, Junjie Fu, Jing Hu, Qingjun You, Xueyan Yao, Dong Hua*, Jian Yin*, Yong Mao*.Chem. Eng. J.,2023,454, 140044.
10. “Recent chemical synthesis and immunological evaluation of glycans related to bacterial lipopolysaccharides”, Chunjun Qin, Guangzong Tian, Jing Hu, Xiaopeng Zou, Jian Yin*.Curr. Opin. Chem. Biol.,2024,78, 102424.
11. “Total synthesis of theHelicobacter pyloriserotype O2 O-antigenα-(1→2)- andα-(1→3)-linked oligoglucosides”, Guangzong Tian, Chunjun Qin, Zhonghua Liu, Dacheng Shen, Xiaopeng Zou, Junjie Fu, Jing Hu, Peter H. Seeberger, Jian Yin*.Chem. Commun.,2020,56, 344-347.
12. “Chemical synthesis of the trisaccharide repeating unit of the O‑antigen ofFusobacterium nucleatumATCC 51191”, Wenbin Sun, Guangzong Tian, Meiru Ding, Xiaopeng Zou, Jing Hu, Jian Yin*.Org. Lett.,2024,26, 321-326.
13. “Immunological exploration ofHelicobacter pyloriserotype O2 O-antigen by using a synthetic glycan library”, Ming Zhao, Guangzong Tian, Chunjun Qin, Xiaopeng Zou, Peter H. Seeberger, Jing Hu*, Jian Yin*.Chin. J. Chem.,2024,42, 243-251.
14. “Stereoselective synthesis and immunological evaluation of common O-antigen ofP. mirabilisOE andP. vulgarisTG103”, Xiaopei Wu, Jinsheng Lai, Kexin Yang, Yunxia Xue, Jinxi Liao, Liming Wang, Jian-song Sun, Jing Hu*, Jian Yin*, Qingju Zhang*.Chin. J. Chem.,2023,41, 535-543.
15. “Synergistic glycosylation as key to the chemical synthesis of an outer core octasaccharide ofHelicobacter pylori”, Xiaopeng Zou, Chunjun Qin, Claney L. Pereira, Guangzong Tian, Jing Hu, Peter H. Seeberger*, Jian Yin*.Chem. Eur. J.,2018,24, 2868-2872.
