一、个人简介
邱立朋,男,1984年10月出生,博士、副教授、硕士生导师,《沈阳药科大学学报》首届青年编委,江苏省药学会海洋药物专委会委员,江苏省预防医学会全球卫生专委会委员。
主要经历:
2011.9-2014.6沈阳药科大学,药剂学,理学博士
2014.6-2022.1江南大学药学院,副教授
2019.9-2021.9山东大学-翔宇药业股份有限公司,博士后。
2021.12-2022.12牛津大学医学部,访问学者
2022.1-至今73882必赢网页版,副教授
二、研究领域
药物新剂型;智能药物递送系统;多糖聚合物纳米载体
三、荣誉奖励
全国挑战杯优秀指导教师
江南大学“青年至善学者”
江南大学教学成果特等奖
江南大学优秀毕业论文指导教师
高等学校科学研究技术进步二等奖
中国商业联合会科技进步一等奖
中国轻工业联合会科技进步二等奖
四、学术成果
(一)代表性项目
[1] 重点研发计划子课题,2021YFC2103100。
[2] 国家自然科学基金青年项目,81503007。
[3] 中国博士后科学基金面上(一等资助)项目,2019M660166。
[4] 江苏省自然科学基金面上项目,BK20201344。
[5] 山东省博士后创新项目,202002039。
[6] 透明质酸冻干制剂的研发,企业项目。
[7] 延胡索乙素纳米微乳的研制,企业项目。
[8] 新型小分子化合物可开发性研究,企业项目。
(二)代表性论文
多年来,围绕多糖生物载体材料合成、智能药物递送系统构建、细胞和动物作用评价等进行研究,以一作/通讯作者在专业期刊发表SCI论文20余篇,其中,一区SCI论文10篇,近5年累积引用约1000次,H指数16。主要代表作如下:
[1] Enhanced Effect of pH-Sensitive Mixed Copolymer Micelles for Overcoming Multidrug Resistance of Doxorubicin. Biomaterials. 2014, 35(37): 9877-9887.
[2] Self-assembled pH-responsive Hyaluronic Acid-g-poly (L-histidine) Copolymer Micelles for Targeted Intracellular Delivery of Doxorubicin. Acta Biomaterialia. 2014, 10 (5): 2024-2035.
[3] cRGDyK modified pH responsive nanoparticles for specific intracellular delivery of doxorubicin. Acta Biomaterialia. 2016, 30: 285-298.
[4] pH-Sensitive degradable polymeric micelles for bio-triggered targeted anti-tumor drug delivery, J Control Release. 2017, 259: e86-e87.
[5] pH-triggered degradable polymeric micelles for targeted anti-tumor drug delivery. Mater Sci Eng C Mater Biol Appl. 2017, 78: 912-922.
[6] Designing heparan sulfate-based biocompatible polymers and their application for intracellular stimuli-sensitive drug delivery. Mater Sci Eng C Mater Biol Appl. 2019, 94: 465-476.
[7] Derma roller® microneedles-mediated transdermal delivery of doxorubicin and celecoxib co-loaded liposomes for enhancing the anticancer effect. Mater Sci Eng C Mater Biol Appl. 2019, 99:1448-1458.
[8] Elucidation of cellular uptake and intracellular trafficking of heparosan polysaccharide-based micelles in various cancer cells. Int J Biol Macromol. 2019, 130:755-764.
[9] Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery. Asian J Pharm Sci. 2020, 15(1): 83-94.
[10] A facile synthesis of uniform hollow MIL-125 titanium-based nanoplatform for endosomal esacpe and intracellular drug delivery. Chem Eng J, 2020, 396: 125246.
[11] Overcoming multidrug resistance by intracellular drug release and inhibiting p-glycoprotein efflux in breast cancer. Biomed Pharmacother, 2021, 134: 111108.
[12] Bacteria-mediated cancer therapies: opportunities and challenges. Biomater Sci. 2021, 9(17): 5732-5744.
[13] Biological role of heparan sulfate in osteogenesis: A review. Carbohydr Polym. 2021, 272: 118490.
[14] Carbon Nitride Nanosheets for Imaging Traceable CpG Oligodeoxynucleotide Delivery. ACS Appl Nano Mater, 2021, 4(8): 8546-8555.
[15] Fabrication of pH/Reduction Sensitive Polyethylene Glycol-Based Micelles for Enhanced Intracellular Drug Release. Pharmaceutics. 2021, 13(9): 1464.
[16] Stimuli-responsive, dual-function prodrug encapsulated in hyaluronic acid micelles to overcome doxorubicin resistance. Acta Biomater. 2021, 140:686-699.
(三)主要授权专利
[1]一种肝素前体多糖聚合物及其制备方法和应用,201811562526.3.
[2]一种肝素衍生物-泊洛沙姆温敏型水凝胶及其制备方法,201810901872.3
[3]一种注射用多功能复合型水凝胶及其制备方法,201810185988.1
[4]一种塞来昔布微晶、负载塞来昔布微晶的温敏性凝胶及其制备方法,202110773477.3
五、联系方式
通讯地址:江苏省无锡市蠡湖大道1800号73882必赢网页版
邮编:214122
邮箱:qiulp@jiangnan.edu.cn
【以上资料更新日期】:2022年2月